Hamari Chemicals Ltd, known at the time as Hama Physical and Chemical Research Institute, was established in December of 1948 in Osaka, Japan. Four years later in 1952, the company was renamed Hamari Chemicals Ltd. Hamari Chemicals has extensive experience as a contract manufacturer of small-molecule actives and intermediates and is capable of multistep small molecule c-GMP synthesis. In addition Hamari offers c-GMP synthesis during pre-clinical stages in which it can perform solubility studies, increase bioavailability and absorption, perform chemical modifications to increase efficacy as well as providing process optimization, process validation, calculating FTE values, and assisting in regulatory filings. Company's current strength is being able to offer custom peptides and asymmetric chiral building blocks using out their own original catalysts and chiral technologies.