Mattioli Engineering developed its first Microdermabrasion System in 1991 and established the company that same year. The company’s extensive experience in the medical and cosmetic field enables the company to develop features, which are protected by patented rights exclusively to Mattioli Engineering. The company' s Transderm Ionto technology is a powered drug delivery system that is indicated for the local administration of ionic drug solutions into the body for medical purposes and can be used as an alternative to injections.