Sopharma Plc engages in the research, engineering, manufacture, and trade in active substances and pharmaceutical forms in Bulgaria and internationally. It offers pharmaceutical products for central nervous system, spasmolytic, vegetotropic, cardiovascular, digestive system, pulmonary system, anti-inflammatory, Oto-Rhino-Laryngologic, dermatology, psychoneurology, analgesics and antipyretics, antiallergy, respiratory, and rheumatology indications. It also provides antibiotics, hormonal, vitamins and minerals, and energizing products. In addition, the company manufactures amorphous silicon dioxide, a raw material for use in the cosmetic and chemical industry. Sopharma Plc has collaboration agreements with GlaxoSmithKline, Novartis, and Janssen-Cilag. The company was founded in 1933 and is headquartered in Sofia, Bulgaria.